You take the T of course!

Boston's public transportation system, the MBTA, (affectionately called "the T" by the locals) will get you just about anywhere you want to go around town, via bus or train. You will have access to  routes, schedules, maps and fare information.

There is also a feature called the trip planner. You can enter your beginning and ending destinations, plus dates and time for your trip.

If you have a particular destination in mind, such as a restaurant or museum, you can ask how to get there by T if you call. Or, your hotel concierge will certainly be able to point you in the right direction!